I am not an interstate person. Interstates make me sleepy. So even if there is something interesting on the side of the road (which is rare along an interstate), I often miss it. Or can't find an appropriate place to pull off to photograph it.
Backroads are my preferred way to go. There is so much more to see. Still, it's easy to just drive by without stopping to investigate or take a photograph. You have to be determined and proactive. You must leave some flex time in your schedule. You should not be in a car with an impatient driver or one who is alarmed by a sudden outburst with instructions to pull over, back there. Better yet, drive yourself.
I had driven past this wonderful old church in Middle Georgia several times on my way to Amelia Island. One day, I finally stopped. That was when I noticed the front door was slightly ajar, so I could take a peek inside (where I discovered it is still occasionally used, despite its deteriorated condition). Later, when I researched this church, I learned that it was built in the late 1800s by freed slaves and their descendants.
Take the backroads from time to time. Build in some flexibility and don't be in such a rush to reach your destination. Let your sense of curiosity lead the way.